HealthONE is the largest healthcare system in the metro Denver area with 8,500 employees and 3,000 affiliated physicians. Named Colorado's 'Best Company for Working Families (2004, 2005, 2006, 2007), the health system was created in 1995 as a 50/50 joint venture between non-profit The Colorado Health Foundation (formerly HealthONE Alliance), Colorado's second largest charitable foundation, and various affiliates of HCA.

HealthONE includes: The Medical Center of Aurora and Centennial Medical Plaza; North Suburban Medical Center; Presbyterian/St. Luke's Medical Center and Rocky Mountain Hospital for Children at Presbyterian/St. Luke's Medical Center; Rose Medical Center; Sky Ridge Medical Center; Spalding Rehabilitation Hospital; Swedish Medical Center and Swedish Southwest ER; 11 ambulatory surgical centers; more than 30 occupational medicine/rehabilitation, Broncos Sports Medicine, specialty, and outpatient diagnostic imaging clinics; and AIRLIFE, which provides critical care air and ground transportation for an eight-state region. .